HYPOCALCEMIC DISORDERS
HYPOCALCEMIC DISORDERS
Dr E.Faraji
MD,Internist,Endocrinologist
Tabriz University of Medical Sciences
Nothing to Declare
Calcium in the Body
- 99% in Bone
- 1% Exchangeable
- 50% Bound
- 50% Ionized
- Strong Extra- to Intracellular Gradiant (10,000:1)
- Calcium Channels
- Intracellular portion 99% Bound
Calcium Regulators
- PTH
- 1,25(OH)2 VitD3
- Calcium
- P
Hypocalcemia
- Acute or Chronic reduction of IONIZED Ca below normal physiologic range
- 8.5 – 10.5 mg/dl Total ca.
- Ionized Ca below 1.2mM/l
- Total Ca influenced by albumin,PH,FFA level,lipid infusions
